Sickle Cell Disease and Exchange Transfusion
نویسندگان
چکیده
منابع مشابه
Chronic intrahepatic cholestasis in sickle cell disease requiring exchange transfusion.
A 15 year old boy with sickle cell disease developed intrahepatic cholestasis. A course of exchange transfusion successfully corrected the extreme hyperbilirubinaemia over one year. Upon stopping the exchange transfusion programme the hyperbilirubinaemia relapsed but transfusion was effective when reinstituted.
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In 1,814 patients with sickle cell disease who had been transfused, the overall rate of alloimmunization to erythrocyte antigens was 18.6%. The rate of alloimmunization in this group appears to be an explicit function of the number of transfusions received because it increases exponentially with increasing numbers of transfusions. Alloimmunization usually occurred with less than 15 transfusions...
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The management of sickle-cell crisis in a pregnant patient by exchange transfusion is described, the procedure leading to immediate and dramatic improvement in the condition. Partial exchange transfusion in three other patients with sickle-cell anaemia, judged by episodes of crisis in previous pregnancies to be at particular risk, is also reported and the value of this method of management disc...
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Sickle cell disease (SCD) is the most commonly inherited hemoglobinopathy in the United States. Blood transfusion is a critical part of the multidisciplinary approach necessary in the management of SCD; however, blood transfusions are not without complications. The successful use of transfusion as a treatment strategy in SCD requires the critical review and knowledge of transfusion methods, gen...
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LTHOUGH IT IS likely that sickle cells have been reA sponsible for morbidity and mortality in humans for thousands of years,' it was not until 1910 that the first description of sickle cell anemia appeared? Subsequently, sickle cell anemia has become the prototype of modern molecular disease, its history tracing the evolution of science and medicine in the 20th century.' Sickle cell disease (SC...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1969
ISSN: 0035-9157
DOI: 10.1177/003591576906200834